today’s genetics lecture on cancer went something like this
familial adenomatous polyposis (FAP): autosomal dominant trait resulting in the development of polyps and benign growths in the colon
• polyps often develop into malignant growths and cause cancer of the colon and/or rectum:
1. mutation in the APC gene on chromosome 5
2. mutation ozone copy of the k-ras proto-oncogene in a polyp cell transforms the polyp into an adenoma; mutations in both alleles of any of several downstream genes (including DCC) leads to formation of late-stage adenomas
3. mutations in both alleles of the p53 gene on chromosome 17 cause the late-stage adenoma to become cancerous
punctuated by gigglesnorts from the guys behind me
“hur hur she said fap”
“HAHA FAP”
“i’ll fap in your colon”
“das gay”

